2. Cardiovascular Disease

Cardiovascular Disease

Cardiovascular Disease

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Cardiovascular diseases (CVDs) are the leading causes of death and disability worldwide. CVDs include diseases of the heart, vascular diseases of the brain and diseases of blood vessels. Caused by atherosclerosis, coronary heart disease and cerebrovascular disease are the most common forms of CVDs. Other less common forms of CVDs include rheumatic heart disease and congenital heart disease. A large percentage of CVDs is preventable through the reduction of behavioral risk factors such as tobacco use, physical inactivity and unhealthy diet. Dietary sodium reduction can alleviate the long-term risk of cardiovascular disease events. Statin therapy is an effective intervention in both the primary and secondary preventions of CVDs in those who are at high risk.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N7971
    2-Hydroxy-1-Methoxyaporphine 33770-27-3 98%
    2-Hydroxy-1-Methoxyaporphine is an alkaloid that can be isolated from Nelumbo nucifera. 2-Hydroxy-1-Methoxyaporphine is the major active ingredient of the Chinese traditional medicine Jiang-Zhi-Ning.
    2-Hydroxy-1-Methoxyaporphine
  • HY-N7991
    Rubiayannone A 517918-25-1 98%
    Rubiayannone A is an anthraquinone glycoside with an antiplatelet aggregation activity.
    Rubiayannone A
  • HY-N8018
    Leucosceptoside A 83529-62-8 98%
    Leucosceptoside A is a phenylethanoid glycoside with anti-hyperglycemic and anti-hypertensive activities. Leucosceptoside A shows inhibitory activity against α-glucosidase and PKCα (IC50 of 19.0 μM).
    Leucosceptoside A
  • HY-N8049
    Urolithin M7 531512-26-2 98%
    Urolithin M7 is an orally active metabolite, which is generated through gut microbiota metabolism. Urolithin M7 inhibits oxidative stress and modulates inflammatory signaling pathways. Urolithin M7 is promising for research of gut microbiota metabolism and cardiovascular diseases.
    Urolithin M7
  • HY-N8086
    Korepimedoside C 205445-00-7 98%
    Korepimedoside C (Epimedin I), a flavonol glycoside, is isolated from the aerial parts of Epimedium koreanum Nakai. Epimedium koreanum Nakai is a famous Chinese herbal medicine for the research of impotence, osteoporosis, immune suppression and cardiovascular diseases.
    Korepimedoside C
  • HY-N8087
    Epimedin K 174286-13-6 98%
    Epimedin K (Korepimedoside B), a flavonol glycoside, is isolated from the aerial parts of Epimedium koreanum Nakai. Epimedium koreanum Nakai is a famous Chinese herbal medicine for the research of impotence, osteoporosis, immune suppression and cardiovascular diseases.
    Epimedin K
  • HY-N8095
    Kushenol N 102490-65-3 98%
    Kushenol N is a prenylated flavonoid that can be isolated from the root of Sophora flavescens. Kushenol N has anti-allergic and vasorelaxation activities.
    Kushenol N
  • HY-N8178
    (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone 849727-88-4 98%
    (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, a homoisoflavonoid, has antiangiogenic activity against human retinal microvascular endothelial cells.
    (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone
  • HY-N8214
    Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside 60778-00-9 98%
    Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside is a bioactive constituent that can be found in the seeds of Lepidium apetalum Willd. Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside exhibits significant triglyceride (TG)-lowering effects in HepG2 cells.
    Isorhamnetin 3-O-β-D-glucose-7-O-β-D-gentiobioside
  • HY-N8218
    Homoeriodictyol 7-O-β-D-glucoside 14982-11-7 98%
    Homoeriodictyol 7-O-β-D-glucoside is a natural platelet-activating factor (PAF) antagonist. Homoeriodictyol 7-O-β-D-glucoside inhibits human and rabbit platelet aggregation induced by PAF, with an IC50 of 0.8 μM.
    Homoeriodictyol 7-O-β-D-glucoside
  • HY-N8444
    Triptoquinone A 142950-86-5 98%
    Triptoquinone A, an interleukin 1 inhibitor, inhibits endomycin (LPS) or interleukin (IL-1β)-promoted induction of nitric oxide synthase (NOS) in vascular smooth muscle, thereby inhibiting Arg-induced vascular relaxation.
    Triptoquinone A
  • HY-N8598
    Caulophine 1159989-19-1 98%
    Caulophine is a fluoroketone alkaloid isolated from Caulophyllum robustum MAXIM. Caulophine has antioxidant activity and the ability to protect cardiomyocytes from oxidative and ischemic damage, providing potential value for coronary heart disease research.
    Caulophine
  • HY-N8653
    11α,12α-Epoxy-3β,23-dihydroxy-30-norolean-20(29)-en-28 186140-36-3 98%
    11α,12α-Epoxy-3β,23-dihydroxy-30-norolean-20(29)-en-28 is a triterpenoid that isolated from Paeonia Lactiflora.
    11α,12α-Epoxy-3β,23-dihydroxy-30-norolean-20(29)-en-28
  • HY-N8706
    Hydrangetin 485-90-5 98%
    Hydrangetin inhibits platelet aggregation. Hydrangetin can be isolated from Zanthoxylum schinifolium.
    Hydrangetin
  • HY-N8754
    (7S)-Dalbergiphenol 52811-31-1 98%
    (7S)-Dalbergiphenol is a cytotoxic compound that can be isolated from Brazilian red propoli. (7S)-Dalbergiphenol inhibits cancer cell viability. Brazilian red propoli has cardioprotective activity.
    (7S)-Dalbergiphenol
  • HY-N8903
    Mumefural 222973-44-6 98%
    Mumefural is a bioactive component of the processed fruit of Prunus mume Sieb. Mumefural inhibits platelet aggregation. Mumefural shows anti-thrombotic effects and ameliorates cognitive impairment.
    Mumefural
  • HY-N9005
    Dysolenticin J 1337973-08-6 98%
    Dysolenticin J has potent vasodilative effects on aortic rings. Dysolenticin J is an alkaloid that can be isolated from Dysoxylum lenticellatum.
    Dysolenticin J
  • HY-N9113
    1,3,5,6-Tetrahydroxyxanthone 5084-31-1 98%
    1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats.
    1,3,5,6-Tetrahydroxyxanthone
  • HY-N9149
    Cryptanoside A 98570-81-1 98%
    Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB.
    Cryptanoside A
  • HY-N9206
    Kimcuongin 1872403-23-0 98%
    Kimcuongin (compound 1)is a coumarin that can be found in Murraya paniculata. Kimcuongin shows vasorelaxant activity with an IC50 value of 37.7 μM. Kimcuongin can be used as a vasodilator.
    Kimcuongin
Cat. No. Product Name / Synonyms Application Reactivity